VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Crab-eating macaque

Scientific Name: Macaca fascicularis

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Primates-> Haplorrhini-> Simiiformes-> Catarrhini-> Cercopithecoidea-> Cercopithecidae-> Cercopithecinae

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Bovine viral diarrhea virus 1

Family: Flaviviridae

Receptor: CD46

Receptor CD46 information

Summary: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1027 2019.11 10X Genomics AorticArtery Normal 4383 Link
Vthunter_1028 2019.11 10X Genomics CoronaryArtery Normal 3606 Link
Vthunter_110069 2019.12 MARS-seq TotalBrain Normal 768 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CD46 in human tissues   [NCBI]

Expression: Ubiquitous expression in adrenal (RPKM 99.0), placenta (RPKM 71.8) and 25 other tissues?

Protein expression of CD46 in human tissues   [Proteinatlas]